Article

Mobilization of antibiotic resistance genes differ by resistance mechanism

2021-01-11

Abstract excerpt

The degree to which antibiotic resistance genes (ARGs) are mobilized by insertion sequence (IS) elements, plasmids, and integrons has a strong association with their likelihood to function as resistance determinants. This stems from genetic decontextualization where strong promoters often present in IS elements and integrons and the copy number effect of plasmids contribute to high expression of accessory genes. H...

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Literature Corpus work: f07fb381-2641-5061-8b05-dc072c79c095
DOI: 10.1101/2021.01.10.426126

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