Article

Clinical implications and genetical insights of SOX6 expression in acute myeloid leukemia

2022-07-12

Abstract excerpt

<h4>Background: </h4> Transcription factor SOX6 belongs to Sry‐related high‐mobility‐group box (SOX) family, has been reported to be downregulated and act as a tumor-suppressor gene in various solid tumors, but in acute myeloid leukemia (AML) is incompletely understood. <h4>Methods: </h4>: The SOX6 expression was analyzed between AML patients and normal controls from public data and our research cohort. Correlatio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f06ee626-bf77-532e-a2ba-a4fe2c16990a
DOI: 10.21203/rs.3.rs-1824554/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Clinical implications and genetical insights of SOX6 expression in acute myeloid leukemiaDOI 10.21203/rs.3.rs-1824554/v1Read

Clinical implications and genetical insights of SOX6 expression in acute myeloid leukemia.Semantic proximity Read

Prognostic significance of SOX2, SOX3, SOX11, SOX14 and SOX18 gene expression in adult de novo acute myeloid leukemia.Semantic proximity Read

Identification and validation of SRY-box containing gene family member SOX30 methylation as a prognostic and predictive biomarker in myeloid malignanciesSemantic proximity Read

SOX6 blocks the proliferation of BCR-ABL1+ and JAK2V617F+ leukemic cellsSemantic proximity Read

Clinical Correlation of Transcription Factor SOX3 in Cancer: Unveiling Its Role in TumorigenesisSemantic proximity Read

Systematic Investigation of the Multifaceted Role of SOX11 in CancerSemantic proximity Read

Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia.Semantic proximity Read

Distinct association of RUNX family expression with genetic alterations and clinical outcome in acute myeloid leukemia.Semantic proximity Read

Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafishSemantic proximity Read

Splicing factor-mediated regulation patterns reveals biological characteristics and aid in predicting prognosis in acute myeloid leukemiaSemantic proximity Read

Advance of SOX Transcription Factors in Hepatocellular Carcinoma: From Role, Tumor Immune Relevance to Targeted TherapySemantic proximity Read

Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia.Semantic proximity Read