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A natural fusion of flavodiiron, rubredoxin, and NADH:rubredoxin oxidoreductase domains is the highly efficient water-forming oxidase of <i>T. vaginalis</i>

2022-02-02

Abstract excerpt

Microaerophilic pathogens such as Giardia lamblia and Trichomonas vaginalis have robust oxygen consumption systems to detoxify oxygen and maintain the intracellular redox balance. This oxygen consumption is a result of the H 2 O-forming NADH oxidase activity of two distinct flavin-containing systems: H 2 O-forming NADH oxidases (NOXes) and multicomponent flavodiiron proteins (FDPs). Both systems are not membra...

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Literature Corpus work
f0480f77-93ad-5c1b-aa25-3dd701518359
DOI
10.1101/2022.02.02.478753
Open publication

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