Article
Highly diverged novel subunit composition of apicomplexan F-type ATP synthase identified from Toxoplasma gondii.
PLoS biology - 1 Jul 2018
Salunke Rahul, Mourier Tobias, Banerjee Manidipa, Pain Arnab, Shanmugam Dhanasekaran
Abstract excerpt
The mitochondrial F-type ATP synthase, a multisubunit nanomotor, is critical for maintaining cellular ATP levels. In T. gondii and other apicomplexan parasites, many subunit components necessary for proper assembly and functioning of this enzyme appear to be missing. Here, we report the identification of 20 novel subunits of T. gondii F-type ATP synthase from mass spectrometry analysis of partially purified...
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