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Article

Purifying selection and adaptive evolution proximate to the zoonosis of SARS-CoV-1 and SARS-CoV-2

2023-08-07

Abstract excerpt

Over the past two decades the pace of spillovers from animal viruses to humans has accelerated, with COVID-19 becoming the most deadly zoonotic disease in living memory. Prior to zoonosis, it is conceivable that the virus might largely be subjected to purifying selection, requiring no additional selective changes for successful zoonotic transmission. Alternatively, selective changes occurring in the reservoir spec...

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Identifiers and source

Literature Corpus work
f042eee4-3d9a-587a-b158-e0f3879cc7e9
DOI
10.1101/2023.08.07.552269
Open publication

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Purifying selection and adaptive evolution proximate to the zoonosis of SARS-CoV-1 and SARS-CoV-2DOI 10.1101/2023.08.07.552269
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