Article

Exploratory Metabolomic and Metagenomic Profiling of Fecal Samples in Isolated REM Sleep Behavior Disorder

2026-08-05

Abstract excerpt

Isolated REM sleep behavior disorder (iRBD) is among the most reliable prodromal markers of α-synucleinopathies, yet accessible biomarkers of phenoconversion risk are lacking and the fecal metabolome remains poorly investigated in this population. In this exploratory, cross-sectional study of 21 iRBD patients and 15 healthy controls, we characterized fecal samples through an integrated multi-omics framework. The f...

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Literature Corpus work: f03b8ba1-c00e-5dc4-9feb-35c2f526ae7f
DOI: 10.20944/preprints202608.0322.v1

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