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Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank

2017-08-10

Abstract excerpt

<h4>Background: </h4> Cognitive ability is a heritable trait with a polygenic architecture, for which several associated variants have been identified using genotype-based and candidate gene approaches. Haplotype-based analyses are a complementary technique that take phased genotype data into account, and potentially provide greater statistical power to detect lower frequency variants. <h4>Methods: </h4>: In the...

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Literature Corpus work
f025ab57-ce49-50c0-8da4-4249f5ac77fa
DOI
10.12688/wellcomeopenres.12171.1
Open publication

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Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK BiobankDOI 10.12688/wellcomeopenres.12171.1
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