Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions.

Translational psychiatry - 13 Dec 2016

Hill W D, Davies G, Harris S E, Hagenaars S P, Liewald D C, Penke L, Gale C R, Deary I J

Abstract excerpt

Differences in general cognitive function have been shown to be partly heritable and to show genetic correlations with several psychiatric and physical disease states. However, to date, few single-nucleotide polymorphisms (SNPs) have demonstrated genome-wide significance, hampering efforts aimed at determining which genetic variants are most important for cognitive function and which regions drive the genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Cognition
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Molecular Biology

Share to Neuropsychological Tests

Share to Problem Solving

Share to Statistics as Topic

Source

Open in PubMed Open full text

Identifiers

PMID: 27959336
DOI: 10.1038/tp.2016.246
PMCID: PMC5290340

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions.PMID 27959336Read ↗

Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regionsSemantic proximity Read ↗

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.Semantic proximity Read ↗

Cognitive Genomics: Recent Advances and Current Challenges.Semantic proximity Read ↗

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N = 112 151) and 24 GWAS consortia.Semantic proximity Read ↗

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia.Semantic proximity Read ↗

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)Semantic proximity Read ↗

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium.Semantic proximity Read ↗

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).Semantic proximity Read ↗

Genomic insights into the shared and distinct genetic architecture of cognitive function and schizophrenia.Semantic proximity Read ↗

The impact of rare protein coding genetic variation on adult cognitive function.Semantic proximity Read ↗

Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151).Semantic proximity Read ↗

Results of a "GWAS plus:" general cognitive ability is substantially heritable and massively polygenic.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.