Article

Protecting Allogeneic Pancreatic Islet Grafts by Engineered Veto

2024-01-07

Abstract excerpt

<h4>Summary</h4> In today’s clinical practice, general immune suppression regimens are used to prevent transplant rejection. Though highly effective, they impair a patient’s protection against infectious challenges. Strategies are being sought that prevent graft rejection without inhibiting beneficial immune functions. One such approach is based on the classical veto effect that employs donor-derived CD8 + T cel...

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Literature Corpus work: efdf05e7-4b31-5a7d-9888-fb31fae1a235
DOI: 10.1101/2024.01.05.574389

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