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Article

The Role of Cutaneous B‐Cells in Hidradenitis Suppurativa: From Preclinical Evidence to Novel Targeted Therapies

1 Sept 2025

Abstract excerpt

Hidradenitis Suppurativa (HS) is a chronic autoinflammatory skin disease of the terminal hair follicle, whose pathogenesis is complex and multifactorial. Alongside a predisposing genetic background, environmental/epigenetic factors, alterations in the skin microbiome, and dysregulation of both innate and adaptive immune responses contribute to the persistent inflammatory network. Despite advancing knowledge, the...

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PMID: 40898716
DOI: 10.1111/exd.70163

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