Article

Multi-Omics and Experimental Validation Reveal the Targets and Mechanisms of Urolithin A in diabetic kidney disease

2026-04-14

Abstract excerpt

<h4>Background: </h4> Urolithin A (UA) has therapeutic potential in diabetic kidney disease (DKD), but its molecular targets and mechanisms remain unclear. <h4>Methods:</h4> Transcriptomic and single-cell datasets were integrated with UA target prediction. Machine learning, ROC analysis, GSEA, immune infiltration, and pseudotime trajectory inference were applied to identify biomarkers and proximal convoluted tubul...

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Literature Corpus work: efb4c78c-60f5-54dc-8f78-6b93cc2fba26
DOI: 10.20944/preprints202604.0890.v1

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