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Multiomics Analyses Identify AKR1A1 as a Biomarker for Diabetic Kidney Disease

23 Feb 2024

Abstract excerpt

Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease. Because many genes associate with DKD, multiomics approaches were used to narrow the list of functional genes, gene products, and related pathways providing insights into the pathophysiological mechanisms of DKD. The Kidney Precision Medicine Project human kidney single-cell RNA-sequencing (scRNA-seq) data set and Mendeley Data on...

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PMID: 38394643
DOI: 10.2337/db23-0540

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