Article

Stimuli-specific senescence of primary human lung fibroblasts modulates alveolar stem cell function

2024-01-29

Abstract excerpt

Aging is the main risk factor for chronic lung diseases (CLDs) including idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD). Accordingly, hallmarks of aging such as cellular senescence are present in different lung cell types such as fibroblasts in these patients. However, whether the senescent phenotype of fibroblasts derived from IPF or COPD patients differs is still unknown. Th...

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Literature Corpus work: ef6487ee-da35-5574-8c4c-efa10f51c7e7
DOI: 10.21203/rs.3.rs-3879423/v1

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