Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis

26 Apr 2018

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing interstitial pneumonia of unknown cause with a median survival of only three years. Little is known about the mechanisms that precede the excessive collagen deposition seen in IPF, but cellular senescence has been strongly implicated in disease pathology. Senescence is a state of irreversible cell-cycle arrest accompanied by an abnormal secretory profile...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to Occupational and environmental lung diseases
Share to Pleural and Pulmonary Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29696986
DOI: 10.1152/ajplung.00037.2018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fibroblast senescence in the pathology of idiopathic pulmonary fibrosisPMID 29696986Read ↗

Fibroblast Senescence in Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Cellular Senescence in Lung FibrosisSemantic proximity Read ↗

Cellular Senescence: The Trojan Horse in Chronic Lung DiseasesSemantic proximity Read ↗

Exploring the Interplay between Cellular Senescence, Immunity, and Fibrosing Interstitial Lung Diseases: Challenges and OpportunitiesSemantic proximity Read ↗

IPF lung fibroblasts have a senescent phenotypeSemantic proximity Read ↗

Mitochondrial dysfunction and alveolar type II epithelial cell senescence: The destroyer and rescuer of idiopathic pulmonary fibrosisSemantic proximity Read ↗

Lung Fibroblasts, Aging, and Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM.Semantic proximity Read ↗

Molecular Mechanisms of Alveolar Epithelial Stem Cell Senescence and Senescence-Associated Differentiation Disorders in Pulmonary FibrosisSemantic proximity Read ↗

Telomere Dysfunction in Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Cellular Senescence in the Lung: The Central Role of Senescent Epithelial CellsSemantic proximity Read ↗

Cellular Senescence in Aging Lungs and DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.