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SPAG1 Expression as a Candidate Predictor of Pathological Lymph Node Metastasis in Prostate Cancer: A Transcriptomic Analysis of The Cancer Genome Atlas Prostate Adenocarcinoma Cohort

2026-06-12

Abstract excerpt

<h4>Background: </h4> /Objectives: Improved preoperative prediction of nodal metastasis in prostate cancer could refine selection for extended pelvic lymph node dissection, a high-morbidity procedure. Sperm-associated antigen 1 (SPAG1) is a candidate marker of nodal status, but its incremental value beyond clinical staging and the associated transcriptional state remain unevaluated. <h4>Methods:</h4> In The Cancer...

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Literature Corpus work: ef06d889-b271-5a78-85de-29fec2a56681
DOI: 10.20944/preprints202606.1026.v1

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