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Article

Personalized Regression Enables Sample-Specific Pan-Cancer Analysis

2018-04-05

Abstract excerpt

In many applications, inter-sample heterogeneity is crucial to understanding the complex biological processes under study. For example, in genomic analysis of cancers, each patient in a cohort may have a different driver mutation, making it difficult or impossible to identify causal mutations from an averaged view of the entire cohort. Unfortunately, many traditional methods for genomic analysis seek to estimate a...

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Literature Corpus work
eeee9ef5-7990-5959-be00-17ec908a9875
DOI
10.1101/294496
Open publication

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