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Deep learning and alignment of spatially-resolved whole transcriptomes of single cells in the mouse brain with Tangram

2020-08-30

Abstract excerpt

Charting a biological atlas of an organ, such as the brain, requires us to spatially-resolve whole transcriptomes of single cells, and to relate such cellular features to the histological and anatomical scales. Single-cell and single-nucleus RNA-Seq (sc/snRNA-seq) can map cells comprehensively 5,6 , but relating those to their histological and anatomical positions in the context of an organ’s common coordinate fr...

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Literature Corpus work
eecd4088-e940-56fd-a7fe-370d34282701
DOI
10.1101/2020.08.29.272831
Open publication

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Deep learning and alignment of spatially-resolved whole transcriptomes of single cells in the mouse brain with TangramDOI 10.1101/2020.08.29.272831
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