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Analytical and Clinical Validation of Direct Detection of Antimicrobial Resistance Markers by Plasma Microbial Cell-free DNA Sequencing

2024-03-18

Abstract excerpt

<h4>ABSTRACT</h4> Sequencing of plasma microbial cell-free DNA (mcfDNA) has gained increased acceptance as a valuable adjunct to standard-of-care testing for diagnosis of infections throughout the body. Here we report the analytical and clinical validation of a novel application of mcfDNA sequencing, the non-invasive detection of seven common antimicrobial resistance (AMR) genetic markers in 18 important pathogens...

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Literature Corpus work
ee7d2253-3ad0-5f4d-b562-05165ba66f01
DOI
10.1101/2024.03.14.24303933
Open publication

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Analytical and Clinical Validation of Direct Detection of Antimicrobial Resistance Markers by Plasma Microbial Cell-free DNA SequencingDOI 10.1101/2024.03.14.24303933
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