Article

Shared Genetic Architecture Between COVID-19 Severity and Alzheimer's Disease Across European and African Ancestries

2025-01-30

Abstract excerpt

The global outbreak of COVID-19 is linked to long-term neurological complications, including an increased risk of Alzheimer’s disease (AD) among older adults. We investigated whether phenotypes of COVID-19 and AD held pathological connections by analyzing the genetic relationship between them. This study explored the association between AD and polygenic risk scores (PRS) of three COVID-19 phenotypes in European an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ee4c6cb7-cd30-5d25-b43f-8d48e6bb9426
DOI: 10.22541/au.173821242.28856771/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Shared Genetic Architecture Between COVID-19 Severity and Alzheimer's Disease Across European and African AncestriesDOI 10.22541/au.173821242.28856771/v1Read

Shared Genetic Architecture Between COVID-19 Severity and Alzheimer's Disease Across European and African AncestriesSemantic proximity Read

Shared genetic architecture of COVID-19 and Alzheimer’s diseaseSemantic proximity Read

Intersection of COVID-19 and Alzheimer's Disease: Genetic Insights and Neuropathological Consequences.Semantic proximity Read

Causal effect of COVID-19 on Alzheimer's disease: A Mendelian randomization study.Semantic proximity Read

Association of COVID-19 with Risk and Progression of Alzheimer's Disease: Non-Overlapping Two-Sample Mendelian Randomization Analysis of 2.6 Million Subjects.Semantic proximity Read

COVID-19 and risk of neurodegenerative disorders: A Mendelian randomization studySemantic proximity Read

Cross-phenotype associations between Alzheimer’s Disease and its comorbidities may provide clues to progressionSemantic proximity Read

COVID ‐19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosisSemantic proximity Read

Genome-wide analysis of genetic predisposition to Alzheimer’s disease and related sex disparitiesSemantic proximity Read

Causal associations and genetic overlap between COVID-19 and intelligence.Semantic proximity Read

Biobank-scale characterization of Alzheimer’s disease and related dementias identifies potential disease-causing variants, risk factors, and genetic modifiers across diverse ancestriesSemantic proximity Read

A Phenome Wide Association Study of Severe COVID-19 Genetic Risk VariantsSemantic proximity Read