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Article

Association of COVID-19 with Risk and Progression of Alzheimer's Disease: Non-Overlapping Two-Sample Mendelian Randomization Analysis of 2.6 Million Subjects.

Journal of Alzheimer's disease : JAD - 1 Jan 2023

Ding Pingjian, Gurney Mark, Perry George, Xu Rong

Abstract excerpt

BACKGROUND: Epidemiological studies showed that COVID-19 increases risk of Alzheimer's disease (AD). However, it remains unknown if there is a potential genetic predispositional effect. OBJECTIVE: To examine potential effects of genetic susceptibility of COVID-19 on the risk and progression of AD, we performed a non-overlapping 2-sample Mendelian randomization (MR) study using summary statistics from genome-wide...

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Identifiers

PMID: 38007657
DOI: 10.3233/JAD-230632
PMCID: PMC11037518

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