Article

DAMPA - accelerated and simplified design of probe panels for targeted metagenomics using pangenome graphs

2026-05-22

Abstract excerpt

Targeted metagenomics, where samples are enriched for multiple organisms of interest using oligonucleotide probes, is a highly efficient sequencing methodology that is becoming standard practice for genomics of viruses and complex polymicrobial samples. Efficient enrichment critically requires probes that capture both conserved and highly diverse genomic regions without loss of sensitivity, and with uniform repres...

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Literature Corpus work: edfc6db7-eef9-57e1-bb24-268ddf43c389
DOI: 10.64898/2026.05.15.26352859

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