Article

Spatially Resolved Epithelial–Immune Heterogeneity Identifies an Endometriosis Subtype with Molecular Features of Endometriosis-Associated Ovarian Cancer

2026-08-25

Abstract excerpt

<title>Abstract</title> <p> Evidence suggests that clear cell and endometrioid ovarian carcinoma may arise from endometriosis. We previously identified that some endometriosis lesions exhibit a “cancer-like” PD-1/PD-L1 positive staining similar to endometriosis-associated ovarian cancers. If this condition is associated with oncogenic signaling and immune tolerance is currently unknown. Using spatial transcripto...

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Literature Corpus work: edd43b93-5ba2-582e-ba3e-d439db56462c
DOI: 10.21203/rs.3.rs-10497180/v1

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