Article

Assessment of human diploid genome assembly with 10x Linked-Reads data

2019-08-08

Abstract excerpt

<h4>Background</h4> Producing cost-effective haplotype-resolved personal genomes remains challenging. 10x Linked-Read sequencing, with its high base quality and long-range information, has been demonstrated to facilitate de novo assembly of human genomes and variant detection. In this study, we investigate in depth how the parameter space of 10x library preparation and sequencing affects assembly quality, on the...

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Literature Corpus work: edcdf60b-8209-52f8-9269-a600863ac2ab
DOI: 10.1101/729608

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