ARKS: chromosome-scale scaffolding of human genome drafts with linked read kmers

Abstract excerpt

<h4>Background</h4> The long-range sequencing information captured by linked reads, such as those available from 10x Genomics (10xG), helps resolve genome sequence repeats, and yields accurate and contiguous draft genome assemblies. We introduce ARKS, an alignment-free linked read genome scaffolding methodology that uses linked reads to organize genome assemblies further into contiguous drafts. Our approach depar...

Topics

Open a Topic to create a Post that cites this publication.

• Algorithms
• Chromosomes, Human
• Genome, Human
• Haplotypes
• Heterozygote
• Polymorphism, Single Nucleotide

Identifiers and source

Literature Corpus work

4e3ff7b3-3d0b-55d3-8f60-126885912868

DOI

10.1101/306902