Association of<i>HLA-DRB1</i>alleles with rheumatoid arthritis in Mediterranean populations: A meta-analysis with regional differences, advanced heterogeneity and evidence quality assessment

Abstract excerpt

<h4>Objective</h4> This meta-analysis evaluates the association between HLA-DRB1 alleles and rheumatoid arthritis (RA) susceptibility in Mediterranean populations, incorporating regional subgroup analyses, heterogeneity assessment, and evidence quality grading. <h4>Methods</h4> A systematic search was conducted across 11 major databases and grey literature sources until December 31, 2023. Eligible studies reported...

Topics

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• Arabs
• Arthritis, Rheumatoid
• Case-Control Studies
• Genetic Association Studies
• HLA-DRB1 Chains
• Odds Ratio
• Protective Factors
• Risk Assessment

Identifiers and source

Literature Corpus work

edb190b9-1cc4-5102-84a2-2fba612ba2c5

DOI

10.1101/2025.04.29.25326652