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Identification of novel vertebral development factors through UK Biobank driven genetic and body imaging analysis reveals markers for back pain

2025-02-14

Abstract excerpt

Numerical variations and transitional anatomy in the human vertebral column, observed in up to 36% of individuals, represent a significant yet understudied aspect of skeletal development with potential effects on multiple physiological systems. Utilising UK Biobank data, we integrated genetic analysis with deep learning-based multi-modal body imaging to investigate genetic factors associated with thoracic and lumb...

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Literature Corpus work: ed364ff6-e723-540e-bd2e-3554e89cbc07
DOI: 10.1101/2025.02.13.25322190

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