Article

The genetic architecture of MRI derived human cervical spinal cord morphology reveals sensory-motor axis and biomarkers of neurological and systemic diseases

2025-08-06

Abstract excerpt

<h4>ABSTRACT</h4> The spinal cord is critical to motor, sensory, autonomic function, and increasingly implicated in neurological disease and human health, yet its genetic architecture remains largely unexplored. We performed the first large-scale phenotyping of the upper cervical spinal cord (C1-C3) structure using brain magnetic resonance imaging from over 40,000 UK Biobank participants, extracting shape metrics...

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Literature Corpus work: bd80eb12-3af0-5aa5-a417-19db42002bb6
DOI: 10.1101/2025.08.05.25333008

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