Article

Multi-ocular Organoids from Human iPS Cells Displayed Retina, Cornea, and RPE Lineages

2021-09-22

Abstract excerpt

<title>Abstract</title> <p>Background: The mammalian eye is a complex organ, comprising different highly specialized tissues derived from various cell linages, including neural ectoderm, surface ectoderm, neural crest and the periocular mesenchyme. Great efforts have been made to design protocols for obtaining ocular cells from human stem cells to model diseases or for regenerative purposes, but the complex cross...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ed2865a6-a2cf-55d1-84b4-ce415e0b9b66
DOI: 10.21203/rs.3.rs-915735/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multi-ocular Organoids from Human iPS Cells Displayed Retina, Cornea, and RPE LineagesDOI 10.21203/rs.3.rs-915735/v1Read

Multiocular organoids from human induced pluripotent stem cells displayed retinal, corneal, and retinal pigment epithelium lineagesSemantic proximity Read

Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cellsSemantic proximity Read

Generating minicorneal organoids from human induced pluripotent stem cellsSemantic proximity Read

Co-ordinated ocular development from human iPS cells and recovery of corneal function.Semantic proximity Read

Cornea organoids from human induced pluripotent stem cellsSemantic proximity Read

Retinal Organoids: A Human Model System for Development, Diseases, and Therapies.Semantic proximity Read

Comprehensive Characterisation of Fetal and Mature Retinal Cell Identity to Assess the Fidelity of Retinal OrganoidsSemantic proximity Read

Retinal organoids derived from rhesus macaque iPSCs undergo accelerated differentiation compared to human stem cellsSemantic proximity Read

Stem Cell-Derived Retinal Pigment Epithelial Layer Model from Adult Human Globes Donated for Corneal Transplants.Semantic proximity Read

Identification and characterization of human retinal stem cells capable of retinal regenerationSemantic proximity Read

Inducing Human Retinal Pigment Epithelium-like Cells from Somatic TissueSemantic proximity Read

Human retinal organoid single-cell atlas allows to reconstruct retinal development at high resolution and identify nature restricted transcriptional states in vitroSemantic proximity Read