Article

3D Microcapsules for Human Bone Marrow Derived Mesenchymal Stem Cell Biomanufacturing in a Vertical-Wheel Bioreactor

2023-02-16

Abstract excerpt

Microencapsulation of human mesenchymal stromal cells (MSCs) via electrospraying has been well documented in tissue engineering and regenerative medicine. Herein, we report the use of microencapsulation, via electrospraying, for MSC expansion using a commercially available hydrogel that is durable, optimized to MSC culture, and enzymatically degradable for cell recovery. Critical parameters of the electrospraying...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ed105a53-683d-5ca2-b13b-fdc89c9ffb77
DOI: 10.1101/2023.02.16.528656

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

3D Microcapsules for Human Bone Marrow Derived Mesenchymal Stem Cell Biomanufacturing in a Vertical-Wheel BioreactorDOI 10.1101/2023.02.16.528656Read

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing PotentialSemantic proximity Read

Mesenchymal stem cell culture within perfusion bioreactors incorporating 3D-printed scaffolds enables improved extracellular vesicle yield with preserved bioactivitySemantic proximity Read

Engineering 3D micro-compartments for highly efficient and scale-independent expansion of human pluripotent stem cells in bioreactorsSemantic proximity Read

Dual production of human mesenchymal stromal cells and derived extracellular vesicles in a dissolvable microcarrier-based stirred culture systemSemantic proximity Read

A simple, cost-effective microfluidic device using a 3D cross-flow T-junction for producing decellularized extracellular matrix-derived microcarriersSemantic proximity Read

Engineered Extracellular Vesicles from Adipose-Derived Stem Cells: Translational Strategies from Genetic Engineering to Scalable ProductionSemantic proximity Read

C-STEM: ENGINEERING NICHE-LIKE MICRO-COMPARTMENTS FOR OPTIMAL AND SCALE-INDEPENDENT EXPANSION OF HUMAN PLURIPOTENT STEM CELLS IN BIOREACTORSSemantic proximity Read

Harnessing hydrodynamics for high-yield production of extracellular vesicles from stem cells spheroids with specific cargo profilingSemantic proximity Read

Matrix Nanoscale Mechanics Regulates Exosome Production by Mesenchymal Stem CellsSemantic proximity Read

Mesenchymal stromal cell encapsulation in uniform chitosan beads using microchannel emulsificationSemantic proximity Read

Alternating 2D and 3D Culture Reduces Cell Size and Extends the Lifespan of Placenta-Derived MSCsSemantic proximity Read

Bioactive Hydrogel Microcapsules for Guiding Stem Cell Fate Decisions by Release and Reloading of Growth FactorsSemantic proximity Read