How Do the Virulence Factors of Shigella Work Together to Cause Disease?

Abstract excerpt

Shigella is a major cause of bacillary dysentery world-wide. It is divided into four species, named S. flexneri, S. sonnei, S. dysenteriae, and S. boydii, which are distinct genomically and in their ability to cause disease. Shigellosis, the clinical presentation of Shigella infection, is characterised by watery diarrhoea, abdominal cramps, and fever. Shigella’s ability to cause disease has been attributed to...

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