Article

Effects of paracetamol (acetaminophen) on gene expression and permeability properties of the rat placenta and fetal brain

2020-08-19

Abstract excerpt

<h4>Background: </h4> Paracetamol (acetaminophen) is widely used in pregnancy and generally regarded as “safe” by regulatory authorities. <h4>Methods: </h4>: Clinically relevant doses of paracetamol were administered intraperitoneally to pregnant rats twice daily from embryonic day E15 to 19 (chronic) or as a single dose at E19 (acute). Control samples were from un-treated age-matched animals. At E19, rats were a...

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Literature Corpus work: ece8bd5a-0aac-50d8-a6fd-411fae6a1ecc
DOI: 10.12688/f1000research.24119.2

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