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Multiplex PCR for simultaneous genotyping of kdr mutations V410L, V1,016I and F1,534C in Aedes aegypti (L.)

2019-12-31

Abstract excerpt

<h4>Background: </h4> Knock down resistance (kdr) is the main mechanism that confers resistance to pyrethroids and DDT. This is a product of nonsynonymous mutations in the he voltage-gated sodium channel (VGSC) gene, these mutations produce a change of a single amino acid which reduces the affinity of the target site for the insecticide molecule. In Mexico, V410L, V1,016I and F1,534C mutations are common in pyreth...

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Literature Corpus work
eccd96c7-45d0-5035-8caa-8e768fcb64a5
DOI
10.21203/rs.2.19782/v1
Open publication

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