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Multiplex PCR for simultaneous genotyping of kdr mutations V410L, V1016I and F1534C in Aedes aegypti (L.).

Parasites & vectors - 25 Jun 2020

Villanueva-Segura Karina, Ponce-Garcia Gustavo, Lopez-Monroy Beatriz, Mora-Jasso Esteban, Perales Lucia, Gonzalez-Santillan Francisco J, Ontiveros-Zapata Kevin, Davila-Barboza Jesus A, Flores Adriana E

Abstract excerpt

BACKGROUND: Knockdown resistance (kdr) is the main mechanism that confers resistance to pyrethroids and DDT. This is a product of non-synonymous mutations in the voltage-gated sodium channel (vgsc) gene, and these mutations produce a change of a single amino acid which reduces the affinity of the target site for the insecticide molecule. In Mexico, V410L, V1016I and F1534C mutations are common in...

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PMID: 32586378
DOI: 10.1186/s13071-020-04193-0
PMCID: PMC7318494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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