Article

Multiplex PCR for simultaneous genotyping of kdr mutations V410L, V1,016I and F1,534C in <i>Aedes aegypti</i> (L.)

2019-12-18

Abstract excerpt

<h4>Background</h4> Knock down resistance (kdr) is the main mechanism that confers resistance to pyrethroids and DDT. This is a product of nonsynonymous mutations in the he voltage-gated sodium channel (VGSC) gene, these mutations produce a change of a single amino acid which reduces the affinity of the target site for the insecticide molecule. In Mexico, V410L, V1,016I and F1,534C mutations are common in pyrethr...

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Literature Corpus work: 5c315370-bdaa-5765-8194-d296d211a027
DOI: 10.1101/2019.12.17.880195

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