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<i>Borrelia burgdorferi</i> loses essential genetic elements and cell proliferative potential during stationary phase in culture but not in the tick vector

2024-10-28

Abstract excerpt

The Lyme disease agent Borrelia burgdorferi is a polyploid bacterium with a segmented genome in which both the chromosome and over 20 distinct plasmids are present in multiple copies per cell. This pathogen can survive at least nine months in its tick vector in an apparent dormant state between blood meals, without losing cell proliferative capability when re-exposed to nutrients. Cultivated B. burgdorferi cells...

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Identifiers and source

Literature Corpus work
ecc34ec0-a836-55bf-aefe-ce2c6d339498
DOI
10.1101/2024.10.28.620338
Open publication

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