Article

Porosome reconstitution therapy: A biologic rescue from cystic fibrosis

2024-09-12

Abstract excerpt

<h4>ABSTRACT</h4> Cystic fibrosis (CF) is a genetic disorder resulting from mutations in the CF Transmembrane Conductance Regulator (CFTR) gene that codes for a chloride transporting channel at the cell plasma membrane. In CF, highly viscous mucus is secreted in the airways preventing its clearance, leading to lung infections and respiratory failure. A major challenge in treating CF patients has been the presence...

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Literature Corpus work: ec87bd1b-29d2-5e5f-8e4a-eb0cf4b78aa3
DOI: 10.1101/2024.09.11.612494

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