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Metabolitin-based molecular drug delivery by targeting GPR158 in glioblastoma

2021-12-13

Abstract excerpt

Glioblastoma multiforme (GBM) is a lethal form of intracranial tumor. One of the obstacles to treat GBM is the blood-brain barrier which limit the transportation of drugs into the tumor site. Here, based on our previous study on metabolitin (MTL) and osteocalcin, we generated a molecular drug delivery system that consisted of metabolitin and small molecules such as fluorescent dye or peptide drugs for diagnosis an...

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Literature Corpus work
ec7b1933-2807-5b50-aeb7-0d8ba8d3619d
DOI
10.1101/2021.12.13.472376
Open publication

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Metabolitin-based molecular drug delivery by targeting GPR158 in glioblastomaDOI 10.1101/2021.12.13.472376
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