Article

Cell-free urine- and plasma DNA mutational analysis predicts neoadjuvant chemotherapy response and outcome in patients with muscle invasive bladder cancer

2022-10-26

Abstract excerpt

<h4>Purpose</h4> Investigate and compare the use of plasma- and urine DNA mutation analysis for predicting neoadjuvant chemotherapy (NAC) response and long-term oncological outcome in patients with muscle invasive bladder cancer. <h4>Experimental Design</h4> Whole exome sequencing of tumor and germline DNA was performed for 92 patients treated with NAC followed by radical cystectomy (RC). A custom NGS panel captur...

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Literature Corpus work: ec72bd57-747e-557f-8ae9-a63df4bafc9c
DOI: 10.1101/2022.10.24.22281440

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