Article

Dissection of barrier dysfunction in organoid-derived human intestinal epithelia induced by <i>Giardia duodenalis</i>

2020-11-17

Abstract excerpt

<h4>Background and aims</h4> The protozoa Giardia duodenalis is a major cause of gastrointestinal illness worldwide, but underlying pathophysiological mechanisms remain obscure, partly due to the absence of adequate cellular models. We aimed to overcome these limitations and to recapitulate the authentic series of events in the primary human duodenal tissue by using the human organoid system. <h4>Methods</h4>...

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Literature Corpus work: ec618462-cc08-5fc6-a6e0-7da95bd019d4
DOI: 10.1101/2020.11.17.384537

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