Article

Adult Canine Intestinal Derived Organoids: A Novel <i>In Vitro</i> System for Translational Research in Comparative Gastroenterology

2018-11-09

Abstract excerpt

<h4>Background</h4> Large animal models, such as the dog, are increasingly being used over rodent models for studying naturally occurring diseases including gastrointestinal (GI) disorders. Dogs share similar environmental, genomic, anatomical, and intestinal physiologic features with humans. To bridge the gap between currently used animal models (e.g. mouse) and humans, and expand the translational potential of...

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Literature Corpus work: 341c97b1-d4d4-5eea-8a66-f6bf813e2bab
DOI: 10.1101/466409

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