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Article

Molecular Functions of Thyroid Hormones and Their Clinical Significance in Liver-Related Diseases

1 Jan 2013

Abstract excerpt

Thyroid hormones (THs) are potent mediators of several physiological processes, including embryonic development, cellular differentiation, metabolism, and cell growth. Triiodothyronine (T3) is the most biologically active TH form. Thyroid hormone receptors (TRs) belong to the nuclear receptor superfamily and mediate the biological functions of T3 via transcriptional regulation. TRs generally form heterodimers...

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PMID: 23878812
DOI: 10.1155/2013/601361

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