Article

Sexual dimorphism in age-related changes in the expression of genes involved into regulation of calcium metabolism in aorta and myocardium of rats

2020-11-03

Abstract excerpt

<title>Abstract</title> <p>Age is the main risk factor for cardiovascular disease development. Understanding of mechanism underlying the vascular and myocardial ageing is necessary both for prevention and for treatment of age-associated diseases. The research aimed to evaluate age-related changes in the transcriptional activity of genes involved in the regulation of Ca2 + signalling – IP3R, RyR, and modulators of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ebf7db5d-b0d2-5691-aa96-3c97dc503bbd
DOI: 10.21203/rs.3.rs-58154/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sexual dimorphism in age-related changes in the expression of genes involved into regulation of calcium metabolism in aorta and myocardium of ratsDOI 10.21203/rs.3.rs-58154/v1Read

Sexual Dimorphism in the Expression of Mitochondria-Related Genes in Rat Heart at Different AgesSemantic proximity Read

Ageing-dependent remodelling of ion channel and Ca<sup>2+</sup>clock genes underlying sino-atrial node pacemakingSemantic proximity Read

Mechanistic Pathways of Sex Differences in Cardiovascular DiseaseSemantic proximity Read

Ageing and longevity genes in cardiovascular diseasesSemantic proximity Read

The role of sex in cardiac function and diseaseThis paper is one of a selection of papers published in this Special Issue, entitled Young Investigator's Forum.Semantic proximity Read

Sexually dimorphic gene expression in the heart of mice and menSemantic proximity Read

Sex modulates the human genome regulatory network during heart failure and aging.Semantic proximity Read

PGC-1α deficiency reveals sex-specific links between cardiac energy metabolism and EC-coupling during development of heart failure in miceSemantic proximity Read

Age-dependent transcriptional alterations in cardiac endothelial cellsSemantic proximity Read

Epigenetic Programming of Synthesis, Release, and/or Receptor Expression of Common Mediators Participating in the Risk/Resilience for Comorbid Stress-Related Disorders and Coronary Artery DiseaseSemantic proximity Read

Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular SenescenceSemantic proximity Read

Rapid Signalling Mechanisms in the Cardiovasculo-Protective Effects of EstrogenSemantic proximity Read