Article
Renal Tubular Cell-Derived Extracellular Vesicles Accelerate the Recovery of Established Renal Ischemia Reperfusion Injury.
Journal of the American Society of Nephrology : JASN - 1 Dec 2017
Dominguez Jesus H, Liu Yunlong, Gao Hongyu, Dominguez James M, Xie Danhui, Kelly K J
Abstract excerpt
Ischemic renal injury is a complex syndrome; multiple cellular abnormalities cause accelerating cycles of inflammation, cellular damage, and sustained local ischemia. There is no single therapy that effectively resolves the renal damage after ischemia. However, infusions of normal adult rat renal cells have been a successful therapy in several rat renal failure models. The sustained broad renal benefit achieved...
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