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Mesenchymal Stem Cell-derived Extracellular Vesicles for Renal Repair

13 Apr 2017

Abstract excerpt

INTRODUCTION: Transplantation of autologous mesenchymal stem cells (MSCs) has been shown to attenuate renal injury and dysfunction in several animal models, and its efficacy is currently being tested in clinical trials for patients with renal disease. Accumulating evidence indicates that MSCs release extracellular vesicles (EVs) that deliver genes, microRNAs and proteins to recipient cells, acting as mediators of...

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PMID: 28403795
DOI: 10.2174/1566523217666170412110724

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