Article

Integration of single-cell RNA and protein data identifies novel clinically-relevant lymphocyte phenotypes in breast cancers

2022-05-31

Abstract excerpt

<h4>Summary</h4> Immune cells are critical determinants of solid tumour aetiology, but the diverse phenotypes of intra-tumoural immune cells remain incompletely characterised. We applied integrated single cell RNA sequencing (scRNA-Seq) and highly multiplexed protein epitope analysis to a cohort of breast cancer samples to resolve cell states within the tumour microenvironment. We reveal novel protein markers for...

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Literature Corpus work: ebab9cf9-401a-50aa-8149-f99401b6649e
DOI: 10.1101/2022.05.31.494081

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