Article

The effect of immunomodulator thymosin α1 on the expression of TNBC PD-L1 through Wnt/β- catenin signaling pathway

2022-05-09

Abstract excerpt

<h4>Purpose: </h4> Explore whether thymosin affects the expression of PD-L1 on the surface of tumor cells, which in turn affects the immunotherapy of triple-negative breast cancer. <h4>Method: </h4> After treating human breast cancer MDA-MB-231 cells with different concentrations of thymosin α1, the PD-L1 expression of the cells was tested for protein and gene. Through bioinformatics analysis, the target gene was...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: eb8b9afc-8936-5f0f-9881-6dcf8e873aeb
DOI: 10.21203/rs.3.rs-1616613/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The effect of immunomodulator thymosin α1 on the expression of TNBC PD-L1 through Wnt/β- catenin signaling pathwayDOI 10.21203/rs.3.rs-1616613/v1Read

Advances in Thymosin β10 Research: Differential Expression, Molecular Mechanisms, and Clinical Implications in Cancer and Other ConditionsSemantic proximity Read

Roles and Mechanisms of β-Thymosins in Cell Migration and Cancer Metastasis: An UpdateSemantic proximity Read

Selected Ideal Natural Ligand Against TNBC by Inhibiting CDC20, Using Bioinformatics and Molecular BiologySemantic proximity Read

Triptonide Effectively Inhibits Triple-Negative Breast Cancer Metastasis Through Concurrent Degradation Of Twist1 And Notch1 OncoproteinsSemantic proximity Read

Discussion On The Mechanism of Que In The Treatment of Breast Neoplasms And Immune Prevention And TreatmentSemantic proximity Read

The Effects of Chemotherapeutic Drugs on PD-L1 Gene Expression in Breast Cancer Cell LinesSemantic proximity Read

Hippo/YAP Signaling Choreographs The Tumor Immune Microenvironment to Promote Triple Negative Breast Cancer Progression Via TAZ/IL-34 AxisSemantic proximity Read

Jack of all trades: thymosin α1 and its pleiotropySemantic proximity Read

Thymosin β4 Regulates Focal Adhesion Formation in Human Melanoma Cells and Affects Their Migration and InvasionSemantic proximity Read

Research Advances in the Role of the Tropomyosin Family in CancerSemantic proximity Read

A Tumor-Penetrating Peptide Modification Enhances the Antitumor Activity of Thymosin Alpha 1Semantic proximity Read

An innovative immunotherapeutic strategy for rheumatoid arthritis: selectively suppressing angiogenesis and osteoclast differentiation by fully human antibody targeting thymocyte antigen-1Semantic proximity Read