Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PER1 as a Tumor Suppressor Attenuated in the Malignant Phenotypes of Breast Cancer Cells

1 Oct 2021

Abstract excerpt

BACKGROUND: Circadian clock genes play a crucial role in physiological and pathological processes, and their aberrant expressions were involved in various human cancers. The objective of this study was to investigate the expression level of Period circadian regulator 1 (PER1), an important circadian clock gene, and its biological roles in the development and progression of breast cancer. METHODS: The expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circadian rhythm and melatonin
Share to Dietary Effects on Health
Share to Plant Molecular Biology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34712059
DOI: 10.2147/ijgm.s328184

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PER1 as a Tumor Suppressor Attenuated in the Malignant Phenotypes of Breast Cancer CellsPMID 34712059Read ↗

THE CIRCADIAN CLOCK GENE<i>PER1</i>SUPPRESSES CANCER CELL PROLIFERATION AND TUMOR GROWTH AT SPECIFIC TIMES OF DAYSemantic proximity Read ↗

PER1 Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Ovarian CancerSemantic proximity Read ↗

Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancySemantic proximity Read ↗

PER3 promoter hypermethylation correlates to the progression of pan-cancerSemantic proximity Read ↗

Elucidation of clinical implications Arising from circadian rhythm and insights into the tumor immune landscape in breast cancerSemantic proximity Read ↗

Remote reprogramming of hepatic circadian transcriptome by breast cancerSemantic proximity Read ↗

Altered circadian genes expression in breast cancer tissue according to the clinical characteristicsSemantic proximity Read ↗

Period 2 Suppresses the Malignant Cellular Behaviors of Colorectal Cancer Through the Epithelial-Mesenchymal Transformation ProcessSemantic proximity Read ↗

Loss of circadian clock gene expression is associated with tumor progression in breast cancerSemantic proximity Read ↗

Association between the Circadian Clock and the Tumor Microenvironment in Breast Cancer.Semantic proximity Read ↗

Loss of PERIOD2 (PER2) induces HO-1-mediated epithelial-mesenchymal transition and cisplatin resistance in Epi-A ovarian cancerSemantic proximity Read ↗

The role of circadian rhythm regulator PERs in oxidative stress, immunity, and cancer developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.