Article

Binding of Hg(I) and Hg(II) to amyloid-beta (Aβ) peptide variants: effects on structure and aggregation

2025-01-24

Abstract excerpt

<title>Abstract</title> <p>Mercury (Hg) exposure is a possible risk factor for Alzheimer´s disease (AD), and some studies have found higher Hg levels in AD patients. Yet, the evidence is inconclusive, and a mechanism linking Hg exposure to AD neuropathology remains to be found. The hallmark of AD brains is deposits of insoluble amyloid plaques consisting mainly of aggregated amyloid-β (Aβ) peptides. Here, we use...

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Literature Corpus work: eb5c250b-7957-52a3-ade4-6678525ea26b
DOI: 10.21203/rs.3.rs-5888115/v1

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