Article

A Simple and New Chromone Congeners Promote Anticancer Activity: Synthesis, Bioactivity Assessment and molecular docking study with ADME profile

2023-12-08

Abstract excerpt

In consideration of the chromones' therapeutic potential and anticancer activity, a new series of chromanone derivatives have been synthesized through a straightforward reaction between 6-formyl-7-hydroxy-5-methoxy-2-methylchromone ( 2 ) and various organic active compounds. The cytotoxic activity of the newly synthesized congeners was investigated against MCF-7 (human breast cancer), HCT-116 (colon cancer), HepG2...

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Literature Corpus work: 5157b904-d125-5581-ad92-33ae75c18c5e
DOI: 10.21203/rs.3.rs-3706913/v1

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