Article

Significance of ABC transporters in fungicide sensitivity and resistance

1997-11-01

Abstract excerpt

ATP-binding cassette (ABC) transporters are members of a protein superfamily which can be responsible for efflux of drugs from cells of target organisms. In this way, the transporters may provide a mechanism of protection against cytotoxic drugs. In laboratory-generated mutants of fungi, overproduction of ABC transporters can cause multi-drug resistance to azoles and other non-related toxicants. The impact of this...

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Literature Corpus work: eaddc878-6c26-524b-b6ab-1027cdf615f9
DOI: 10.1002/(sici)1096-9063(199711)51:3<271::aid-ps642>3.0.co;2-#

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